Wednesday, May 6, 2009

Canadian scientists complete genetic sequencing of A/H1N1 virus

Special Report: World Tackles A/H1N1 Flu

OTTAWA, May 6 (Xinhua) -- Canadian scientists have
completed a genetic sequencing of the A/H1N1 flu viruses that have appeared in
Mexico and Canada and confirmed that they are of the same strain, public health
officials said Wednesday.

The sequencing, which took place at the National
Microbiology Laboratory in Winnipeg and was completed in less than a week, has
eliminated a genetic mutation to explain why Mexican cases of the virus have
been more severe than in other countries.

"We are continuing our analysis, but essentially what
it appears to suggest is that there is nothing at the genetic level that
differentiates this virus that we've got from Mexico and those from Nova Scotia
and Ontario that explains the apparent differences in disease severity between
Mexico and Canada and the United States," Frank Plummer of the National
Microbiology Laboratory told a news conference on Wednesday.

Scientists cannot yet say why the cases in Mexico
have been much more severe than elsewhere, but one theory is that the patients
had underlying medical conditions that increased their susceptibility to the
virus.

This is the world's first sequencing of the new
virus, marking a "significant milestone" in studying the virus, the scientists
said.

The findings will help scientists eventually
understand how the virus originated, how it spreads and how it may change over
time, laying foundation for the development of a vaccine, scientists said.

The lab has submitted the sequencing to GenBank, a
public database where genetic sequencing information can be studied and compared
by scientists around the world, Plummer said.

The World Health Organization (WHO) confirmed on
Tuesday a total of 1,490 laboratory tested H1N1 flu cases from 21 countries,
including 30 deaths.

In Canada, the number of confirmed cases rose to 165 on Tuesday. All cases appear to be mild, with the exception of a girl who was hospitalized in Edmonton, Alberta, due to severe symptoms. 



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